Millicent Wanyama, MBChB, MMed
Nominated From: University of Washington
Research Site: Moi University
Research Area: Sickle Cell Disease
Primary Mentor: Dr. Anjuli Wagner
Research Project
Acceptability and feasibility of newborn screening for Sickle Cell Disease and Sickle Cell Trait in Western Kenya
Majority of children with Sickle Cell Disease (SCD) in Sub-Saharan Africa will die before celebrating their 5th birthday if no intervention is provided. World Health Organization (WHO) recommends newborn screening (NBS) as one of the early interventions to reduce morbidity and mortality associated with SCD. NBS programs for SCD have however not been implemented in Kenya posing a challenge in comprehensive care for children with SCD. This study will address research gaps in SCD care by assessing factors associated with acceptability and feasibility of newborn screening for SCD and trait among parents/caregivers of newborns and the healthcare providers. We will also determine the prevalence of SCD and trait among the newborns.
Research Significance
For successful management of SCD, correct diagnosis has to be established early in life, preferably during the newborn period .NBS allows for early diagnosis and initiation of prophylactic antibiotics and immunizations which help prevent severe bacterial sepsis in affected children and thus increasing their chances of survival. This research study will help provide actionable information on the need and process of scaling up impactful and sustainable NBS programs for SCD.
Publications
Mentors
